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Updated: May 12, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
Published on: February 1, 2016
[Positron emission tomography/magnetic resonance: Present and future]
A A Kohan1, J L Vercher Conejero, M C Gaeta
1Departamento de Radiología, University Hospitals Case Medical Center/Case Western Reserve University, Cleveland, Ohio, USA.
Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) offers advanced diagnostic imaging by combining molecular and tissue resolution. This review explores its clinical applications and potential to improve upon PET/CT, particularly in reducing radiation exposure.
Area of Science:
- Medical Imaging
- Radiochemistry
- Biophysics
Context:
- The integration of Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) presents a novel hybrid imaging modality.
- PET/MRI combines PET's molecular imaging capabilities with MRI's superior soft tissue contrast and multiparametric analysis.
- The clinical impact of PET/CT in oncology, neurology, and cardiology highlights the potential of hybrid imaging.
Purpose:
- To review the theoretical applications and emerging clinical roles of PET/MRI.
- To evaluate the evidence supporting PET/MRI's advantages over existing imaging techniques.
- To discuss the challenges, particularly MRI-based attenuation correction, and practical experiences with PET/MRI.
Summary:
- PET/MRI merges PET's radiotracer-based molecular detection with MRI's detailed anatomical and functional information.
- Key challenges include developing accurate MRI-based attenuation correction methods for quantitative PET imaging.
- Initial studies suggest PET/MRI can replace PET/CT in certain applications, reducing ionizing radiation exposure.
Impact:
- PET/MRI holds promise for advancing diagnostic imaging, offering new insights in oncology, neurology, and cardiology.
- The modality has the potential to improve diagnostic accuracy and patient outcomes by providing complementary molecular and anatomical data.
- Further research and clinical validation are essential to fully realize the benefits of PET/MRI in medical diagnostics.
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