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[Experiences with the p-HEMA posterior chamber lens]
D T Pham1, J Wollensak, E Welzl-Hinterkörner
1Augenklinik, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg der Freien Universität, Berlin.
Fortschritte Der Ophthalmologie : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|January 1, 1990
Summary
Poly(2-hydroxyethyl methacrylate) (p-HEMA) intraocular lenses (IOLs) show excellent biocompatibility with no severe adverse reactions. However, moderate clouding and decentration limit their routine use.
Area of Science:
- Ophthalmology
- Biomaterials Science
- Materials Engineering
Context:
- Review of 120 poly(2-hydroxyethyl methacrylate) (p-HEMA) intraocular lenses (IOLs) implanted over two years.
- Evaluation of clinical outcomes and biocompatibility of p-HEMA IOLs.
Purpose:
- To assess the clinical performance and safety of p-HEMA IOLs.
- To determine the suitability of p-HEMA IOLs for routine implantation.
Summary:
- p-HEMA IOLs demonstrated excellent biocompatibility, with no instances of posterior synechia or severe anterior chamber reactions.
- Moderate, visually insignificant diffuse clouding of the IOLs was observed in some cases.
- IOL decentration occurred in 21 eyes, and low mechanical stability was noted.
Impact:
- The findings suggest that while p-HEMA IOLs exhibit good biocompatibility, their current limitations in mechanical stability and optical clarity hinder widespread clinical adoption.
- Further research and material improvements may be necessary for p-HEMA IOLs to become a standard IOL option.