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Related Experiment Video

Updated: May 12, 2026

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

Surgery for GEP-NETs.

Ulrich Knigge1, Carsten Palnæs Hansen

  • 1Department of Gastrointestinal Surgery C, Neuroendocrine Tumor Centre of Excellence, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. ulrich.knigge@rh.regionh.dk

Best Practice & Research. Clinical Gastroenterology
|April 16, 2013
PubMed
Summary

Surgery offers the only potential cure for gastroentero-pancreatic (GEP) neuroendocrine tumors (NET) and neuroendocrine carcinomas (NEC). Achieving complete or near-complete resection (R0/R1) makes surgery the primary treatment, requiring lifelong follow-up at specialized centers.

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Area of Science:

  • Oncology
  • Surgical Gastroenterology
  • Endocrinology

Background:

  • Gastroentero-pancreatic (GEP) neuroendocrine tumors (NET) and neuroendocrine carcinomas (NEC) are rare neoplasms.
  • Complete surgical resection is the only curative treatment modality for these tumors.

Purpose of the Study:

  • To outline the surgical and interventional procedures for GEP-NET.
  • To emphasize the critical role of surgery as a first-line treatment.
  • To highlight the necessity of lifelong follow-up for patients.

Main Methods:

  • Review of surgical and interventional procedures for GEP-NET.
  • Emphasis on achieving R0/R1 resection.
  • Discussion of post-operative management and follow-up protocols.

Related Experiment Videos

Last Updated: May 12, 2026

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
05:16

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors

Published on: February 19, 2022

Main Results:

  • Surgery is the sole potentially curative treatment for GEP-NET and NEC.
  • R0/R1 resection is the primary goal for surgical intervention.
  • Specialized NET centers are crucial for lifelong patient management.

Conclusions:

  • Surgical resection should be considered the first-line treatment for GEP-NET and NEC when achievable.
  • Lifelong follow-up at specialized centers is essential for optimal patient outcomes.