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Published on: June 14, 2021
[Annular keratopigmentation (PresbyRing®) for treating presbyopia: postmortem animal feasibility study]
1Expert Vision Center, 6, rue Simonis, 67100 Strasbourg, France. francisferrari@me.com
Journal Francais D'Ophtalmologie
|April 16, 2013
Summary
Annular keratopigmentation (PresbyRing®) shows promise for treating presbyopia by creating an intrastromal ring with pigment. This initial feasibility study in pig eyes yielded encouraging results for improving near and intermediate vision.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Vision Science
Background:
- Annular keratopigmentation (PresbyRing®) is a novel technique creating an intrastromal ring using a femtosecond laser and pigment injection.
- The ring's internal diameter is designed to function as a pinhole, enhancing near/intermediate vision in the non-dominant eye with minimal impact on distance vision.
Purpose of the Study:
- To assess the feasibility of annular keratopigmentation (PresbyRing®) in a postmortem animal model.
- To evaluate the efficacy of pigment injection for creating a functional intrastromal ring.
Main Methods:
- Five pig eyes were used for a postmortem feasibility study.
- Treatment involved the Visumax® laser's Intra Corneal Ring program (ICR®) and EU-approved Biochromaderm® dye.
Main Results:
- Spectral domain OCT confirmed complete dye opacity.
- Histological analysis revealed a continuous pigmented layer without stromal diffusion.
- Further in-vivo studies are needed to confirm dye rinsing possibility.
Conclusions:
- This study represents the first experimental combination of an intracorneal pinhole for presbyopia and corneal tattooing.
- The initial postmortem animal study for annular keratopigmentation (PresbyRing®) produced encouraging results.
- Further in-vivo animal and human studies are required for confirmation.
