Related Experiment Videos

Preoperative symptom duration predicts success in relieving abdominal pain caused by biliary dyskinesia in a

Jeremy J Johnson1, Tabitha Garwe, Nicholas Katseres

  • 1University of Oklahoma College of Medicine, Department of Surgery, Oklahoma City, OK 73104, USA. Jeremy-j-johnson@ouhsc.edu

Insights

Laparoscopic cholecystectomy (LC) effectively relieves biliary dyskinesia (BD) symptoms. Pediatric patients with symptoms lasting less than 12 months pre-surgery show the highest likelihood of symptom relief.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Biliary System Disorders

Background:

  • Biliary dyskinesia (BD) is a functional gallbladder disorder.
  • Laparoscopic cholecystectomy (LC) is a common treatment for symptomatic BD.

Purpose of the Study:

  • To identify factors predicting symptom relief after LC in pediatric patients with BD.
  • To determine the impact of preoperative symptom duration on surgical outcomes.

Main Methods:

  • A case-control study was conducted on pediatric patients diagnosed with BD.
  • Patients with symptom resolution were controls; those without were cases.
  • Demographic and clinical variables were analyzed, focusing on preoperative symptom duration and comorbidities.

Main Results:

  • Of 50 eligible patients, 43 had symptom resolution (controls) and 7 did not (cases).
  • Preoperative symptom duration was the only significant predictor of symptom relief after adjusting for comorbidities.
  • 96% of patients with symptoms <12 months experienced relief, versus 70% with symptoms ≥12 months.

Conclusions:

  • Laparoscopic cholecystectomy (LC) is an effective treatment for biliary dyskinesia (BD).
  • Pediatric patients with preoperative symptoms for less than 12 months are more likely to achieve symptom relief post-surgery.
Abstract

Related Concept Videos

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Depolarizing Blockers: Pharmocokinetics01:19

Depolarizing Blockers: Pharmocokinetics

Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...