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Preoperative symptom duration predicts success in relieving abdominal pain caused by biliary dyskinesia in a
Jeremy J Johnson1, Tabitha Garwe, Nicholas Katseres
1University of Oklahoma College of Medicine, Department of Surgery, Oklahoma City, OK 73104, USA. Jeremy-j-johnson@ouhsc.edu
Insights
Laparoscopic cholecystectomy (LC) effectively relieves biliary dyskinesia (BD) symptoms. Pediatric patients with symptoms lasting less than 12 months pre-surgery show the highest likelihood of symptom relief.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Biliary System Disorders
Background:
- Biliary dyskinesia (BD) is a functional gallbladder disorder.
- Laparoscopic cholecystectomy (LC) is a common treatment for symptomatic BD.
Purpose of the Study:
- To identify factors predicting symptom relief after LC in pediatric patients with BD.
- To determine the impact of preoperative symptom duration on surgical outcomes.
Main Methods:
- A case-control study was conducted on pediatric patients diagnosed with BD.
- Patients with symptom resolution were controls; those without were cases.
- Demographic and clinical variables were analyzed, focusing on preoperative symptom duration and comorbidities.
Main Results:
- Of 50 eligible patients, 43 had symptom resolution (controls) and 7 did not (cases).
- Preoperative symptom duration was the only significant predictor of symptom relief after adjusting for comorbidities.
- 96% of patients with symptoms <12 months experienced relief, versus 70% with symptoms ≥12 months.
Conclusions:
- Laparoscopic cholecystectomy (LC) is an effective treatment for biliary dyskinesia (BD).
- Pediatric patients with preoperative symptoms for less than 12 months are more likely to achieve symptom relief post-surgery.
Purpose:
The objective of this study was to identify factors associated with symptom relief in pediatric patients treated with laparoscopic cholecystectomy (LC) for biliary dyskinesia (BD).
Methods:
This was a case-control study of pediatric patients diagnosed with BD between January 2004 and June 2011. Controls were patients with symptom resolution and cases were patients who did not experience symptom relief.
Results:
Fifty patients met study eligibility, of whom 43 were controls and 7 were cases. Mean follow-up for the cohort was 26.5months. Unadjusted comparisons suggested no significant differences (p>0.05) between the two groups in the distribution of demographic and clinical variables with the exception of preoperative duration of symptoms and presence of comorbidity. After adjusting for comorbidities, the only significant predictor associated with the resolution of symptoms after surgery was preoperative duration of symptoms (OR, 0.37; 95% CI, 0.15-0.94); 96% of patients with symptoms<12months had symptom relief versus 70% with symptoms≥12months.
Conclusion:
Symptoms associated with BD can be successfully relieved with LC. These data suggest patients with preoperative symptoms for less than 12months are the most likely to have symptom relief after surgery.
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