The granulocyte response of Bulinus africanus to infection with compatible and non-compatible trematode parasites

The granulocyte response of B. africanus was investigated after infection with either a compatible or a non-compatible trematode parasite. In both experiments a decrease in the granulocyte numbers was observed 7 days post-infection. This was maintained for 20 days. An observation made after 42 days showed that the numbers had recovered to normal. The granulocyte numbers of snails previously infected with S. mansoni (non-compatible) also showed a decrease 7 days after a reinfection. In this case, however, recovery of the numbers was apparent 14 days later. No sporocyst material was present in the head-foot areas of the snail 12 h post-penetration, indicating that they were already destroyed by the snails defence system.