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Updated: May 12, 2026

Dissection of Saccharomyces Cerevisiae Asci
Published on: May 19, 2009
[Saccharomyces cerevisiae infections]
Cristine Souza Goebel1, Flávio de Mattos Oliveira, Luiz Carlos Severo
1Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul, Rio Grande do Sul, Brasil; Departamento de Métodos Diagnósticos, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brasil.
Invasive infections by Saccharomyces cerevisiae, a common yeast, are increasing. This study reviewed 6 cases in Brazil over 10 years, highlighting predisposing factors and treatment outcomes.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Clinical Microbiology
Background:
- Saccharomyces cerevisiae is a common yeast found in industry and human mucosal colonization.
- Invasive infections caused by S. cerevisiae have shown a significant increase in recent decades.
- Understanding the epidemiology and clinical impact of S. cerevisiae infections is crucial.
Purpose of the Study:
- To investigate the incidence and characteristics of Saccharomyces cerevisiae infections.
- To evaluate S. cerevisiae infections in a hospital setting in southern Brazil.
- To analyze a 10-year period of S. cerevisiae infections from 2000 to 2010.
Main Methods:
- Retrospective review of medical records.
- Analysis of patient data including demographics and clinical presentation.
- Identification of predisposing factors and treatment strategies for S. cerevisiae infections.
Main Results:
- Six cases of S. cerevisiae infection were identified in patients aged 10-84 years.
- Infections were diagnosed in urine, blood, ascitic fluid, peritoneal dialysis fluid, and esophageal biopsy samples.
- Common predisposing factors included cancer, transplantation, surgery, renal failure, and immunosuppression; mortality rate was 50%.
Conclusions:
- Emerging fungal infections like S. cerevisiae require increased vigilance, especially in immunocompromised or critically ill patients.
- Prompt and accurate diagnosis of S. cerevisiae infections is vital for effective therapeutic decision-making.
- Further epidemiological studies and antifungal efficacy research are needed for optimal patient management.
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