Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Basilar membrane nonlinearity determines auditory nerve rate-intensity functions and cochlear dynamic range.

G K Yates1, I M Winter, D Robertson

  • 1Department of Physiology, University of Western Australia, Nedlands.

Hearing Research
|May 1, 1990
PubMed
Summary

Auditory nerve response variations stem from basilar membrane nonlinearity. This nonlinearity compresses the cochlea's wide dynamic range, impacting loudness perception.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Orthostatic intolerance in Behcet's disease.

Autonomic neuroscience : basic & clinical·2001
Same author

Familial orthostatic tachycardia due to norepinephrine transporter deficiency.

Annals of the New York Academy of Sciences·2001
Same author

The Ca(2+) status of the endoplasmic reticulum is altered by induction of calreticulin expression in transgenic plants.

Plant physiology·2001
Same author

Can simultaneous inhibition of seedling growth and stimulation of rhizosphere bacterial populations provide evidence for phytotoxin transfer from plant residues in the bulk soil to the rhizosphere of sensitive species?

Journal of chemical ecology·2001
Same author

Gene pill patents a surprise for gene therapy.

Nature biotechnology·2001
Same author

Origin of the noradrenergic innervation of the superior olivary complex in the rat.

Journal of chemical neuroanatomy·2001

Area of Science:

  • Auditory Neuroscience
  • Bioacoustics
  • Physiology

Background:

  • Previous work identified a novel auditory-nerve rate-intensity function (straight type) and its correlation with threshold and spontaneous rate.
  • Auditory nerve fibers exhibit diverse rate-intensity functions, suggesting underlying physiological variations.

Purpose of the Study:

  • To elucidate the origin of variations in auditory-nerve rate-intensity functions.
  • To investigate the role of basilar membrane nonlinearity in shaping these functions.
  • To derive and validate the basilar membrane's input-output function.

Main Methods:

  • Compared auditory-nerve rate-intensity functions at characteristic and tail frequencies.
  • Utilized tail-frequency functions as calibration to derive basilar membrane input-output functions at characteristic frequencies.

Related Experiment Videos

  • Compared derived basilar membrane functions with direct measurements of basilar membrane motion.

    • Main Results:

    • Rate-intensity functions are identical at low firing rates but diverge at higher rates, correlating with characteristic frequency.
    • Derived basilar membrane input-output functions are simple and consistent with direct measurements.
    • Basilar membrane nonlinearity compresses the cochlea's 120 dB dynamic range to 30-35 dB.

    Conclusions:

    • Basilar membrane nonlinearity is the primary source of variations in auditory-nerve rate-intensity functions.
    • The derived basilar membrane input-output functions align with psychoacoustic loudness estimation studies.
    • This nonlinear compression is crucial for auditory processing and perception.