Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
Humoral Immune Responses01:36

Humoral Immune Responses

Overview
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Frustrated, hopeless and hesitant: Understanding doctors' learned attitudes and emotions toward vaccine hesitancy through socialisation theory.

Social science & medicine (1982)·2026
Same author

Trust in government, public health authorities, health scientists and medical care providers and COVID-19 vaccines among Canadian adults.

Scientific reports·2026
Same author

Individual and Environmental Correlations with Vaccination Status in Canada: The COHESION study.

Journal of urban health : bulletin of the New York Academy of Medicine·2026
Same author

Adults' intentions to vaccinate children against measles in Canada: findings from a national survey.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2026
Same author

Measuring the long-term impact of the COVID-19 pandemic on HPV vaccination in Quebec, Canada: A cohort study from the Canadian immunization research network.

Canadian journal of public health = Revue canadienne de sante publique·2026
Same author

Beyond seeking information: Lessons learned from a qualitative investigation of the information practices of parents about COVID-19 vaccination in Canada.

Human vaccines & immunotherapeutics·2026

Related Experiment Video

Updated: May 12, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Vaccine hesitancy: an overview.

Eve Dubé1, Caroline Laberge, Maryse Guay

  • 1Centre de recherche du CHU de Québec; Québec, QC Canada; Institut national de santé publique du Québec (INSPQ); Québec, QC Canada; Université Laval; Québec City, QC Canada.

Human Vaccines & Immunotherapeutics
|April 16, 2013
PubMed
Summary

Vaccine hesitancy, a growing concern, threatens public health by reducing vaccination rates and increasing disease outbreaks. Understanding its causes and individual decision-making factors is crucial for successful immunization programs.

Keywords:
decision-makingpsychosocial factorsreviewsocio-cultural factorsvaccinationvaccine-hesitancy

More Related Videos

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

Related Experiment Videos

Last Updated: May 12, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
07:44

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

Intralymphatic Immunotherapy and Vaccination in Mice
07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

Area of Science:

  • Public Health
  • Epidemiology
  • Behavioral Science

Background:

  • Vaccination is a highly effective public health intervention.
  • A growing segment of the population perceives vaccines as unsafe or unnecessary.
  • Declining confidence in vaccines poses a significant threat to immunization program success.

Purpose of the Study:

  • To provide an overview of vaccine hesitancy.
  • To characterize the phenomenon of vaccine hesitancy.
  • To explore potential causes for increased vaccine hesitancy in developed nations.
  • To examine determinants of individual vaccination decisions.

Main Methods:

  • Literature review of vaccine hesitancy.
  • Analysis of factors contributing to vaccine hesitancy.
  • Exploration of individual decision-making processes regarding vaccination.

Main Results:

  • Vaccine hesitancy is a complex issue with multifaceted causes.
  • Lack of confidence in vaccines is linked to decreased vaccine coverage.
  • Increased vaccine hesitancy correlates with a higher risk of vaccine-preventable disease outbreaks.

Conclusions:

  • Addressing vaccine hesitancy is critical for maintaining herd immunity.
  • Understanding the drivers of vaccine hesitancy is essential for public health strategies.
  • Further research into individual decision-making can inform targeted interventions.