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Related Concept Videos

Urinary Bladder01:23

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
Nursing Assessment of the Genitourinary System II: Inspection and Palpation01:26

Nursing Assessment of the Genitourinary System II: Inspection and Palpation

The nursing assessment of the genitourinary (GU) system involves a systematic inspection and palpation to identify abnormalities in the kidneys, bladder, and surrounding structures.InspectionMouth: Inspect for signs of kidney dysfunction, such as stomatitis (inflammation of the mouth) and ammonia breath, which may occur in advanced kidney disease due to the buildup of urea, breaking down into ammonia.Skin: Check for pallor, which could indicate anemia caused by kidney disease. Look for...
Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Disorders of the Urinary System01:20

Disorders of the Urinary System

The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...

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Related Experiment Video

Updated: May 12, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
07:48

An Orthotopic Bladder Cancer Model for Gene Delivery Studies

Published on: December 1, 2013

Bladder cancer.

Peter E Clark1, Neeraj Agarwal, Matthew C Biagioli

  • 1Vanderbilt-Ingram Cancer Center.

Journal of the National Comprehensive Cancer Network : JNCCN
|April 16, 2013
PubMed
Summary
This summary is machine-generated.

Bladder cancer, specifically urothelial carcinoma, is a common diagnosis. These updated NCCN Guidelines offer recommendations for managing bladder cancer, including chemotherapy principles.

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An Orthotopic Model of Murine Bladder Cancer
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An Orthotopic Model of Murine Bladder Cancer

Published on: February 6, 2011

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Last Updated: May 12, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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An Orthotopic Model of Murine Bladder Cancer
09:07

An Orthotopic Model of Murine Bladder Cancer

Published on: February 6, 2011

Area of Science:

  • Oncology
  • Urology

Background:

  • Bladder cancer is the fourth most common cancer in the U.S.
  • Urothelial carcinoma is the predominant subtype originating in the urinary bladder.

Purpose of the Study:

  • To provide updated NCCN Clinical Practice Guidelines for Oncology (NCCN Guidelines).
  • To offer recommendations for the diagnosis and management of urothelial carcinoma of the bladder, encompassing both non-muscle-invasive and muscle-invasive stages.

Main Methods:

  • The guidelines were developed based on current evidence and expert consensus.
  • Extensive reorganization and updates were implemented, particularly concerning chemotherapy management principles.

Main Results:

  • The updated guidelines address the diagnosis and management of bladder cancer.
  • Key updates focus on the principles of chemotherapy for urothelial carcinoma.

Conclusions:

  • These NCCN Guidelines provide a comprehensive resource for healthcare professionals managing bladder cancer.
  • The updated recommendations aim to improve patient outcomes through optimized diagnosis and treatment strategies, especially regarding chemotherapy.