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Updated: May 12, 2026

Using In Vitro Live-cell Imaging to Explore Chemotherapeutics Delivered by Lipid-based Nanoparticles
Published on: November 1, 2017
Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression
Laura K Moore1, Edward K Chow2, Eiji Osawa3
1Department of Biomedical Engineering Northwestern University Evanston, Illinois, 60208, USA.
Abstract:
Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.
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