Related Experiment Video
Updated: May 12, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
Spontaneous rupture of the non-gravid uterus
Leong Chee Weng1, Tulsi Menon, Graham Hool
1Royal Perth Hospital, Perth, Western Australia, Australia. Dleong87@gmail.com
Abstract:
A 71-year-old woman presents with acute onset abdominal pain with sepsis. Initial workup with an abdominal CT scanning revealed intraperitoneal air with an enlarged uterus and thickened small bowel loops. Haemodynamic instability with sepsis prompted urgent laparotomy. At laparotomy, spontaneous perforation of the uterus was identified. The cause was due to infarction of the myometrium. This occurred on a background of not having any previous instrumentation of the uterus.
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