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Late recurrence of basaloid carcinoma initially treated as a small cell lung cancer

Vladimir Shumaster1, Jason W Bae, Scott N Gettinger

  • 1Section of Thoracic Surgery, Yale University School of Medicine and Yale-New Haven Hospital, New Haven, CT, USA.

Journal of Thoracic Disease
|April 16, 2013
PubMed

Keywords:
Basaloid lung cancerchemotherapylung cancersmall cell lung cancer

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Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
Cancer stem cells are thought to originate from tissue-specific normal stem cells or progenitor cells. The normal stem cells usually reside in...