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Published on: June 4, 2017
Insect allergy in children
John W Tan1, Dianne E Campbell
1Department of Allergy and Immunology, Children's Hospital Westmead; Discipline of Paediatric and Child Health, University of Sydney, Sydney, New South Wales, Australia.
Insights
Insect stings can cause allergic reactions, ranging from local swelling to life-threatening anaphylaxis. Venom immunotherapy is recommended only for children experiencing systemic reactions, not large local ones.
Area of Science:
- Allergy and Immunology
- Pediatric Allergy
- Toxicology
Background:
- Allergic reactions to insect bites and stings are frequent, with presentations varying from localized responses to anaphylaxis.
- In pediatric populations, large local reactions are the most common manifestation of insect stings.
- Hymenoptera insects (bees, wasps, ants) are primary culprits for insect-induced anaphylaxis, though fewer allergic children experience this compared to adults.
Purpose of the Study:
- To review the presentation and management of allergic reactions to insect stings in children.
- To differentiate between local and systemic reactions and their implications for treatment.
- To clarify the indications for venom immunotherapy in pediatric patients.
Main Methods:
- Clinical review of allergic reactions to insect stings in children.
- Emphasis on diagnostic importance of patient history over laboratory tests.
- Evaluation of treatment strategies, including venom immunotherapy.
Main Results:
- Large local reactions are the most common presentation in children.
- Diagnosis of anaphylaxis relies heavily on clinical history due to unreliable laboratory tests.
- Venom immunotherapy is effective but indicated only for systemic reactions, not large local reactions.
Conclusions:
- Venom immunotherapy is not necessary for children with large local reactions to insect stings.
- Management decisions should be guided by reaction severity and clinical history.
- Further research may refine diagnostic and therapeutic approaches for pediatric insect sting allergies.
Abstract:
Allergic reactions to insect bites and stings are common, and the severity of reactions range from local reaction to anaphylaxis. In children, large local reaction to bites and stings is the most common presentation. Stings from insects of the order Hymenoptera (bees, wasps and ants) are the most common cause of insect anaphylaxis; however, the proportion of insect allergic children who develop anaphylaxis to an insect sting is lower than that of insect allergic adults. History is most important in diagnosing anaphylaxis, as laboratory tests can be unreliable. Venom immunotherapy is effective, where suitable allergen extract is available, but is only warranted in children with systemic reactions to insect venom. Large local reactions are at low risk of progression to anaphylaxis on subsequent stings, and hence, venom immunotherapy is not necessary.
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