Related Experiment Video
Updated: May 12, 2026
09:32
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
Temporal patterns and mechanisms of epilepsy surgery failure
Imad Najm1, Lara Jehi, Andre Palmini
1Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA. najmi@ccf.org
Epilepsia
|April 17, 2013
Summary
Epilepsy surgery outcomes can be improved by understanding early versus late seizure recurrence. Early failures suggest issues with epileptogenic zone resection, while late recurrences may indicate new seizure focus development.
Area of Science:
- Neurology
- Neurosurgery
- Epileptology
Background:
- Epilepsy surgery is a key treatment for medically refractory focal epilepsy.
- Despite advanced localization techniques, surgical outcomes remain suboptimal for many patients.
- Long-term data reveal two distinct patterns of seizure recurrence: early and late.
Related Concept Videos
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:22Epilepsy ll: Types
Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.