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Related Concept Videos

The Scientific Method01:32

The Scientific Method

The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
Phosphodiester Linkages01:01

Phosphodiester Linkages

Overview
Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
Phosphodiester Bonds Link Nucleotides Together
DNA and RNA are polynucleotides or long chains of nucleotides that are linked together. A nucleotide is...
X-linked Traits01:19

X-linked Traits

In most mammalian species, females have two X sex chromosomes and males have an X and Y. As a result, mutations on the X chromosome in females may be masked by the presence of a normal allele on the second X. In contrast, a mutation on the X chromosome in males more often causes observable biological defects, as there is no normal X to compensate. Trait variations arising from mutations on the X chromosome are called “X-linked”.
Levels of Organization01:09

Levels of Organization

Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
Inclusive Fitness00:57

Inclusive Fitness

Most altruistic behavior—in which one animal helps another at a cost to themselves—occurs between relatives. Scientists think these altruistic behaviors evolved because they increase the inclusive fitness of the animal providing help.
Genetic Lingo01:11

Genetic Lingo

Overview

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Related Experiment Video

Updated: May 12, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Large and linked in scientific publishing.

Laurie Goodman1, Scott C Edmunds, Alexandra T Basford

  • 1GigaScience, BGI-Hong Kong Co, Ltd, 16 Dai Fu Street, Tai Po Industrial Estate, NT, Hong Kong. laurie@gigasciencejournal.com.

Gigascience
|April 17, 2013
PubMed
Summary
This summary is machine-generated.

GigaScience is a new open-access journal for large biological and biomedical datasets. It links publications to a database for data sharing, reuse, and reproducibility.

More Related Videos

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
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Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

Related Experiment Videos

Last Updated: May 12, 2026

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
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Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

Area of Science:

  • Biological sciences
  • Biomedical sciences
  • Big data research

Background:

  • Scientific publishing traditionally separates data from publications.
  • Large datasets are increasingly common in biological and biomedical research.
  • Challenges exist in data sharing, reuse, and reproducibility.

Purpose of the Study:

  • Announce the launch of GigaScience, a novel open-access journal.
  • Establish a new model for publishing research involving large datasets.
  • Promote enhanced data accessibility and scientific reproducibility.

Main Methods:

  • Publishing research articles alongside a directly linked database.
  • Hosting all relevant research data within the journal's infrastructure.
  • Assigning Digital Object Identifiers (DOIs) to hosted data for citable access.

Main Results:

  • Facilitating rapid release and broader use of large-scale datasets.
  • Improving the reproducibility of scientific findings through direct data access.
  • Enabling easier connections between scientific analyses and their underlying data.

Conclusions:

  • GigaScience offers a platform for transparent and reproducible big data research.
  • The journal aims to advance biological and biomedical sciences through open data practices.
  • Direct data-publication links and DOIs foster deeper data interpretation and future analysis.