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External Anatomy of the Kidney01:21

External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
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Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
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Published on: June 21, 2024

Metanephric adenofibroma.

Robert M Turner Ii1, Jeffrey J Tomaszewski, Janelle A Fox

  • 1Department of Urology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15213, USA.

The Canadian Journal of Urology
|April 17, 2013
PubMed
Summary
This summary is machine-generated.

A rare benign kidney tumor, metanephric adenofibroma, was diagnosed in a 10-year-old boy after flank pain. This stromal-epithelial tumor may represent a mature form of Wilms' tumor.

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Area of Science:

  • Pediatric oncology
  • Renal pathology
  • Surgical oncology

Background:

  • Wilms' tumor is the most common pediatric renal malignancy.
  • Metanephric adenofibroma is a rare benign tumor of the kidney.
  • Distinguishing benign from malignant renal masses in children is crucial for appropriate management.

Observation:

  • A 10-year-old boy presented with left flank pain after a fall.
  • Computed tomography (CT) imaging revealed a 5 cm left upper pole renal mass.
  • Surgical intervention involved a partial nephrectomy.

Findings:

  • Histopathological examination confirmed the renal mass as a metanephric adenofibroma.
  • Metanephric adenofibroma is a benign stromal-epithelial tumor.
  • This tumor is hypothesized to be a hyperdifferentiated, mature variant of Wilms' tumor.

Implications:

  • Accurate diagnosis of metanephric adenofibroma is essential to avoid overtreatment.
  • Understanding the relationship between metanephric adenofibroma and Wilms' tumor can refine diagnostic criteria.
  • This case highlights the importance of comprehensive histopathological analysis in pediatric renal masses.