Ischaemic heart disease in the ageing woman

Sofia A Papadopoulou1, Juan Carlos Kaski

  • 1Cardiovascular Sciences Research Centre, St George's University of London, Cranmer Terrace, London SW17 0RE, UK.

Insights

Women face higher cardiovascular disease mortality than men, often due to underestimated risks and delayed diagnosis. This leads to less aggressive treatment and poorer outcomes for women with heart disease.

Area of Science:

  • Cardiology
  • Public Health
  • Gender Studies

Background:

  • Cardiovascular disease (CVD) is a leading global cause of death, with women experiencing higher mortality rates than men since 1984.
  • Gender-specific differences in symptom presentation and underestimation of CVD risk in women contribute to delayed diagnosis and underuse of medical services.
  • Misperceptions of female protection against heart disease lead to underestimation of risk, impacting healthcare-seeking behavior and treatment intensity.

Purpose of the Study:

  • To review gender-specific differences in the epidemiology, diagnosis, and management of ischaemic heart disease (IHD).
  • To highlight the impact of ageing and menopause on IHD in women.
  • To address the underestimation of heart disease risk and its consequences in women.

Main Methods:

  • Review of epidemiological data on cardiovascular disease mortality in men and women.
  • Analysis of healthcare-seeking behavior and diagnostic timelines for men and women.
  • Examination of treatment strategies and outcomes in relation to gender and age.

Main Results:

  • Women experience greater mortality from cardiovascular disease compared to men.
  • Delays in diagnosis and less intensive resource utilization are observed in women.
  • Underestimation of risk and less aggressive treatment strategies contribute to poorer outcomes for women.

Conclusions:

  • Gender-specific factors significantly influence cardiovascular disease outcomes.
  • Addressing underestimation of risk and improving diagnostic and treatment timeliness for women is crucial.
  • Ageing and menopause are critical factors in the management of ischaemic heart disease in women.

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