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Updated: May 12, 2026

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
Published on: May 2, 2025
Pain associated with negative pressure wound therapy
1Florence Nightingale School of Nursing, King's College, London, UK.
Negative pressure wound therapy (NPWT) can cause pain, impacting patient quality of life. This review found limited evidence on pain management strategies for NPWT, highlighting a need for more research.
Area of Science:
- Wound Care
- Pain Management
- Medical Technology
Background:
- Negative pressure wound therapy (NPWT) is a widely used treatment for complex wounds.
- Anecdotal reports suggest pain is a significant side effect of NPWT.
- This pain can negatively affect patient quality of life and treatment adherence.
Purpose of the Study:
- To review the existing literature on pain management for patients receiving NPWT.
- To identify NPWT administration methods that may minimize patient pain.
- To assess the current evidence base for guiding clinical practice.
Main Methods:
- A literature search was conducted across CINAHL, BNI, Embase, and Medline databases.
- Studies were included if they addressed pain in patients undergoing NPWT.
- Ten studies met the inclusion criteria for this review.
Main Results:
- The reviewed studies indicate potential areas for pain management research in NPWT.
- However, the current evidence is insufficient to make definitive recommendations.
- Further high-quality research is needed to establish best practices.
Conclusions:
- More research is required to develop effective pain management strategies for NPWT.
- Addressing NPWT-associated pain could improve patient outcomes and adherence.
- Current evidence does not support specific administration techniques for pain reduction.
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