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Updated: May 12, 2026

Immunolabelling Myofiber Degeneration in Muscle Biopsies
Published on: December 5, 2019
A microthymoma and no germinal centre in myasthenia gravis
Masatsugu Hamaji1, Paul A Vanderlaan, David J Sugarbaker
1Division of Thoracic Surgery, The Brigham and Women's Hospital, Boston, MA, USA.
Abstract:
A 43-year-old woman with a 1-year history of generalized myasthenia gravis was referred for a video-assisted thorascopic surgery thymectomy. The preoperative chest computed tomography revealed mild diffuse thymic hyperplasia. Pathology of the resected thymus gland revealed a 6-mm World Health Organization (WHO) Type AB microthymoma without thymic germinal centres. The entity of microthymoma was reviewed with a focus on examining the pathological and therapeutic differences between thymic hyperplasia and microscopic thymoma.
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