Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Temporal correlations in sensory-synaptic interactions: example in crayfish stretch receptors.

L C Barrio1, W Buño

  • 1Neurofisiología, Instituto Cajal, Madrid, Spain.

Journal of Neurophysiology
|June 1, 1990
PubMed
Summary

Inhibitory postsynaptic potential (IPSP) barrages influence crayfish stretch receptor coding by altering spike timing. Regular IPSPs create alternations and sliding, while irregular IPSPs increase interval irregularities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Muscarinic Receptors, from Synaptic Plasticity to its Role in Network Activity.

Neuroscience·2020
Same author

Histopathology of alkaptonuric ochronosis.

Prensa medica argentina·2010
Same author

The cinematographer in the teaching of embryology.

Anales de la Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay·2010
Same author

Fibrillar Structures In Adenohypophysis Cells.

Archivos. Sociedad de Biologia de Montevideo·2010
Same author

Direct determinations of internal hydrostatic pressure of Fundulus egg.

The Biological bulletin·2010
Same author

Voltage-gated potassium conductances in Gymnotus electrocytes(AB).

Neuroscience·2007

Area of Science:

  • Neuroscience
  • Computational Biology
  • Sensory Physiology

Background:

  • Sensory receptors encode stimuli through patterns of neural impulses.
  • Inhibitory postsynaptic potentials (IPSPs) play a crucial role in modulating neuronal activity and information processing.
  • Understanding how IPSPs affect sensory coding is vital for deciphering neural computations.

Purpose of the Study:

  • To investigate the impact of inhibitory postsynaptic potential (IPSP) barrages on the coding of sinusoidal length inputs in crayfish stretch receptors (RM1 and RM2).
  • To analyze the temporal correlations between sensory stimuli, pre- and postsynaptic spikes, and the influence of IPSPs on these patterns.

Main Methods:

  • Recording from slowly (RM1) and rapidly (RM2) adapting crayfish stretch receptors.

Related Experiment Videos

  • Applying sinusoidal length stimuli.
  • Analyzing temporal correlations between sensory stimuli, pre- and postsynaptic spikes, and IPSPs.
  • Quantifying phase (phi) and cophase (theta) relationships between IPSPs and spikes.

    • Main Results:

    • IPSP barrages generally increased postsynaptic interval durations in both RM1 and RM2.
    • Regular IPSPs induced epochs of inhibitory (S) and postsynaptic (R) spikes with S/R ratios (1:1, 1:2, 2:1) and 'alternations'.
    • Sudden 'jumps' in interval durations and gradual 'sliding' (phi increase-theta decrease) were observed with 1:1 and 1:2 ratios, while sliding disappeared with 2:1 ratios.
    • Irregular IPSPs increased postsynaptic interval irregularities and eliminated alternations, with phase values irregularly distributed.

    Conclusions:

    • IPSP barrages significantly alter the temporal coding of sensory stimuli in crayfish stretch receptors.
    • The pattern of IPSPs (regular vs. irregular) dictates the nature of the coding modifications, including alternations, sliding, and interval irregularities.
    • These findings provide insights into the mechanisms by which inhibitory inputs shape sensory information processing in the nervous system.