Related Experiment Video
Updated: May 12, 2026

Enumeration of Major Peripheral Blood Leukocyte Populations for Multicenter Clinical Trials Using a Whole Blood Phenotyping Assay
Published on: September 16, 2012
Impact of providing fee data on laboratory test ordering: a controlled clinical trial
Leonard S Feldman1, Hasan M Shihab, David Thiemann
1Division of General Internal Medicine, The Johns Hopkins University School of Medicine, 600 N Wolfe St, Nelson 215, Baltimore, MD 21287, USA. LF@jhmi.edu
Insights
Displaying laboratory test costs to inpatient providers reduced test orders by 8.6%. This intervention may decrease unnecessary diagnostic tests and lower healthcare spending.
Area of Science:
- Health Economics
- Clinical Operations
- Medical Informatics
Background:
- Inpatient care providers frequently order laboratory tests without awareness of their associated costs.
- High rates of laboratory test ordering contribute to increased healthcare expenditures.
Purpose of the Study:
- To evaluate the impact of presenting laboratory test fees at the point of order entry on test ordering frequency.
- To determine if this intervention can reduce the number of ordered laboratory tests in a tertiary care hospital without disrupting the ordering workflow.
Main Methods:
- A controlled clinical trial was conducted at a tertiary care hospital.
- 61 diagnostic laboratory tests were randomized to either display fees (active arm) or not (control arm) within the computerized provider order entry system.
- Data on test orders, frequency per patient-day, and charges were collected during baseline and intervention periods.
Main Results:
- Tests with displayed fees (active arm) showed an 8.59% decrease in ordering frequency (3.72 to 3.40 tests/patient-day).
- Tests without displayed fees (control arm) experienced a 5.64% increase in ordering frequency (1.15 to 1.22 tests/patient-day).
- The difference in ordering trends between active and control tests was statistically significant (P < .001).
Conclusions:
- Presenting fee data to providers at the time of order entry led to a modest reduction in laboratory test ordering.
- This intervention holds potential for decreasing the frequency of inappropriately ordered diagnostic tests.
- Implementing cost transparency at order entry may be a viable strategy for cost containment in healthcare settings.
Importance:
Inpatient care providers often order laboratory tests without any appreciation for the costs of the tests.
Objective:
To determine whether we could decrease the number of laboratory tests ordered by presenting providers with test fees at the time of order entry in a tertiary care hospital, without adding extra steps to the ordering process.
Design:
Controlled clinical trial.
Setting:
Tertiary care hospital.
Participants:
All providers, including physicians and nonphysicians, who ordered laboratory tests through the computerized provider order entry system at The Johns Hopkins Hospital.
Intervention:
We randomly assigned 61 diagnostic laboratory tests to an "active" arm (fee displayed) or to a control arm (fee not displayed). During a 6-month baseline period (November 10, 2008, through May 9, 2009), we did not display any fee data. During a 6-month intervention period 1 year later (November 10, 2009, through May 9, 2010), we displayed fees, based on the Medicare allowable fee, for active tests only.
Main Outcome Measures:
We examined changes in the total number of orders placed, the frequency of ordered tests (per patient-day), and total charges associated with the orders according to the time period (baseline vs intervention period) and by study group (active test vs control).
Results:
For the active arm tests, rates of test ordering were reduced from 3.72 tests per patient-day in the baseline period to 3.40 tests per patient-day in the intervention period (8.59% decrease; 95% CI, -8.99% to -8.19%). For control arm tests, ordering increased from 1.15 to 1.22 tests per patient-day from the baseline period to the intervention period (5.64% increase; 95% CI, 4.90% to 6.39%) (P < .001 for difference over time between active and control tests).
Conclusions And Relevance:
Presenting fee data to providers at the time of order entry resulted in a modest decrease in test ordering. Adoption of this intervention may reduce the number of inappropriately ordered diagnostic tests.
Related Concept Videos
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Blinding
Bioavailability Study Design: Healthy Subjects Versus Patients
Therapeutic Drug Monitoring: Affecting Factors

