Related Experiment Video
Updated: May 12, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Decreased prevalence of high-risk human papillomavirus infection is associated with obesity
1Department of Obstetrics and Gynecology, Konyang University Hospital, Konyang University College of Medicine, Daejon, Republic of Korea.
Purpose Of Investigation:
Obesity is correlated with low education, low economic status, and lower rates of Pap smears, which are known as socio-demographic risk factors for cervical cancer. However, the association between obesity and high-risk human papillomavirus (HR-HPV) infection, the necessary cause of cervical cancer, and its related precursors, is not established.
Materials And Methods:
The authors examined the association between obesity and HR-HPV infection in 6,868 patients, who participated in annual health examinations at the Kangbuk Samsung Hospital in Seoul, Korea, from January through December 2007.
Results:
The prevalence of HR-HPV infection was 14.8%. Women infected with HR-HPV had a lower body mass index (BMI), when compared with non-infected women. After adjustment for alcohol intake, cigarette smoking, and marital status, HR-HPV infection was found to be negatively associated with BMI. When the analysis was stratified according to BMI, the risk of HR-HPV infection was significantly lower among those who were overweight (OR = 0.817, 95% CI = 0.680-0.982), or obese (OR = 0.688, 95% CI = 0.556-0.851), when compared with women with normal weight.
Conclusion:
HR-HPV infection was associated with obesity defined by BMI, with a lower prevalence of infection observed in obese women.
Related Concept Videos
Obesity
Cancer Prevention
Some...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Stress Prevention and Stress Management Techniques IV
Psychoneuroimmunology: Diabetes and Cancer
