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The correlation between aortic stiffness and left ventricular mass index in hypertensive patients: a cardiac MRI

Anuchit Wongphen1, Thananya Boonyasirinant

  • 1Division of Cardiology, Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|April 18, 2013
PubMed

Insights

This study found no significant correlation between left ventricular mass index and aortic stiffness in hypertensive patients. Aortic stiffness was, however, significantly correlated with age.

Area of Science:

  • Cardiovascular Medicine
  • Medical Imaging
  • Hypertension Research

Background:

  • Increased left ventricular (LV) mass and aortic stiffness are independent cardiovascular event predictors.
  • Prior studies suggest a correlation between LV hypertrophy and aortic stiffness, but data in hypertensive patients are limited.
  • Cardiac MRI offers a promising method for LV mass assessment.

Purpose of the Study:

  • To assess the correlation between LV mass and aortic stiffness in hypertensive patients using cardiac MRI.
  • To investigate the relationship between LV mass index and aortic pulse wave velocity (PWV).

Main Methods:

  • 113 hypertensive patients underwent cardiac MRI.
  • LV mass index was calculated using the summation of multiple slice technique.
  • Aortic stiffness was measured as PWV, calculated from the transit time between the mid-ascending and mid-descending aorta.

Main Results:

  • No significant correlation was observed between PWV and LV mass index (r = 0.085, p = 0.37).
  • Aortic stiffness showed a significant positive correlation with age (r = 0.469, p < 0.001).

Conclusions:

  • No significant correlation was found between LV mass index and aortic stiffness in this cohort of hypertensive patients.
  • The lack of correlation might be attributed to relatively less severe LV hypertrophy in the study population.
Abstract

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