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Optimal Blood Pressure Goals in Patients With Hypertension at High Risk for Cardiovascular Events
1Department of Medicine, Division of Cardiology, New York Medical College, Valhalla, NY.
Insights
For patients younger than 80 with hypertension and high cardiovascular risk, blood pressure should be <140/90 mm Hg. For those 80 and older, systolic blood pressure goal is 140-145 mm Hg if tolerated.
Area of Science:
- Cardiology
- Nephrology
- Endocrinology
- Neurology
Background:
- Hypertension poses significant cardiovascular risks.
- High-risk patients include those with coronary artery disease, diabetes mellitus, chronic kidney disease, stroke, or heart failure.
Purpose of the Study:
- To review evidence supporting specific blood pressure goals for high-risk hypertensive patients.
- To guide treatment strategies for preventing cardiovascular events.
Main Methods:
- Analysis of existing epidemiologic and clinical trial data.
- Discussion of studies focusing on patients with comorbidities like coronary artery disease, diabetes, kidney disease, stroke, and heart failure.
Main Results:
- Evidence supports a blood pressure goal of <140/90 mm Hg for hypertensive patients younger than 80 at high cardiovascular risk.
- For patients aged 80 years and older, a systolic blood pressure goal of 140-145 mm Hg is recommended if tolerated.
Conclusions:
- Lowering blood pressure to <140/90 mm Hg is crucial for high-risk patients under 80.
- Age-adjusted systolic blood pressure targets are necessary for older adults to minimize cardiovascular event risk.
Abstract:
Existing epidemiologic and clinical trial data suggest that the blood pressure in patients with hypertension at high risk for cardiovascular events because of coronary artery disease, diabetes mellitus, chronic kidney disease, stroke, or heart failure should be reduced to <140/90 mm Hg in patients younger than 80 years and the systolic blood pressure be reduced to 140-145 mm Hg if tolerated in patients aged 80 years and older. Studies from patients with coronary artery disease, diabetes mellitus, chronic kidney disease, stroke, and heart failure will be discussed that support a blood pressure goal of <140/90 mm Hg in patients younger than 80 years at high risk for cardiovascular events.
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