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Related Experiment Video

Updated: May 12, 2026

Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device

Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device

Published on: July 29, 2016

Amniotic band sequence--a debilitating syndrome.

R Uma¹, A Garg, S K Patnaik

¹Department of Pediatrics, 7 Air Force Hospital, Kanpur Cantt, 91 208004, India.

JNMA; Journal of the Nepal Medical Association

|April 18, 2013

Summary

This summary is machine-generated.

A baby diagnosed with amniotic band sequence presented with limb malformations including amputations and hypoplasia. Distinguishing these congenital anomalies is crucial for genetic counseling and recurrence risk assessment.

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Area of Science:

Medical Genetics
Developmental Biology
Obstetrics

Background:

Amniotic band sequence (ABS) is a rare congenital disorder.
It can cause a range of fetal malformations, primarily affecting limbs.

Observation:

A male neonate delivered via Cesarean section presented with multiple grooves and hypoplasia of the left hand's fingers.
The neonate also had bilateral congenital amputations of the great toes.

Findings:

The observed limb anomalies, asymmetrical involvement, and presence of amniotic bands led to a diagnosis of amniotic band sequence.
Congenital amputations were differentiated from congenital hypoplasia/aplasia.

Implications:

Accurate diagnosis of amniotic band sequence is vital for understanding prognosis.
Distinguishing between amputation and hypoplasia/aplasia is essential for genetic counseling and recurrence risk evaluation.