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Hypolipidemic activity of the chitooligosaccharides from Clanis bilineata (Lepidoptera), an edible insect
Zhenqiang Xia1, Jinhua Chen, Shengjun Wu
1School of Marine Science and Technology, HuaiHai Institute of Technology, 59 Cangwu Road, Xinpu 222005, China.
Abstract:
Clanis bilineata (CB) is an edible insect, and CB larvae (CBL) are widely consumed in China, yielding a large number of CBL skin (CBLS). In this study, chitooligosaccharides (COS) from CBLS were prepared and their hypolipidemic activity was determined in rats. Thirty-six male Sprague-Dawley rats in 3 groups were fed diets containing either high fat (HF) or COS, or a normal fat (NF) for 6 weeks. Compared with HF group, COS group showed decreased body weight gain, plasma triacylglycerol (TG), total cholesterol (TC), and plasma low-density lipoprotein cholesterol (LDL-C) level. Fecal fat and cholesterol of the COS group were higher than those of NF and HF groups. The results indicated that COS could be a suitable alterative hypolipidemic source for humans.
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