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Pregnancy outcome in Budd Chiari Syndrome--a tertiary care centre experience
Neelam Aggarwal1, Vanita Suri, Seema Chopra
1Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, PGIMER, Chandigarh, 160012, India.
Background:
Pregnancy management is a crucial issue in women with Budd-Chiari Syndrome (BCS) and there are no established guidelines on the management.
Aim:
To report our experience of pregnancy outcome with BCS.
Material And Methods:
We report outcome of 13 pregnancies in three women, with favourable outcome after the diagnosis of the condition and its treatment using intervention to bypass obstruction and anticoagulant therapy during pregnancy.
Results:
Three women had a total of 13 pregnancies; three after the diagnosis and decompressive treatment of the disease. Disease was diagnosed during index pregnancy in two women. Anticoagulation was given in all the three pregnancies (Robertson et al., Br J Haematol, 132:171-196, 2006). Pregnancies prior to diagnosis and treatment resulted in a live birth.
Conclusion:
Pregnancy does not seem to be a contraindication in well treated and controlled BCS. Maternal outcome is good with close multidisciplinary surveillance. Foetal outcome, however, may still be poor due to underlying prothrombotic condition.