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Related Experiment Video

Updated: May 12, 2026

An Atmospheric Pressure Plasma Setup to Investigate the Reactive Species Formation

An Atmospheric Pressure Plasma Setup to Investigate the Reactive Species Formation

Published on: November 3, 2016

Sensitive low-pressure dielectric barrier discharge ion source.

Masuyuki Sugiyama¹, Shun Kumano, Kazushige Nishimura

¹Hitachi, Ltd., Central Research Laboratory, Kokubunji-shi, Tokyo, Japan. masuyuki.sugiyama.bp@hitachi.com

Rapid Communications in Mass Spectrometry : RCM

|April 18, 2013

Summary

A new low-pressure dielectric barrier discharge ionization (LP-DBDI) method offers significantly higher sensitivity for mass spectrometry. This novel soft ionization technique achieved up to 44 times greater sensitivity compared to conventional atmospheric pressure chemical ionization.

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Area of Science:

Analytical Chemistry
Mass Spectrometry
Plasma Physics

Background:

A novel soft ionization method, low-pressure dielectric barrier discharge ionization (LP-DBDI), was developed.
This technique utilizes a dielectric barrier discharge (DBD) for high ionization and transmission efficiency.

Purpose of the Study:

To introduce and evaluate the performance of the LP-DBDI source.
To compare the sensitivity of LP-DBDI with conventional atmospheric pressure chemical ionization (APCI).

Main Methods:

Mass spectrometric detection was performed using an ion trap mass spectrometer in positive ion mode.
The LP-DBDI source was directly compared against a conventional APCI source.
Samples were analyzed after vaporization and introduction via an air flow of 1.5 L/min.

Main Results:

Mass spectra were successfully acquired for methyl salicylate, 2-undecanone, and methamphetamine using LP-DBDI, primarily showing protonated molecules.
The LP-DBDI source demonstrated significantly enhanced sensitivity, achieving 44x for methyl salicylate and 39x for 2-undecanone compared to APCI.
Minor fragmentation was observed, characteristic of soft ionization.

Conclusions:

LP-DBDI is an effective soft ionization method with minimal fragmentation, comparable to APCI.
The LP-DBDI source offers a substantial sensitivity improvement, approximately 40-fold higher than conventional APCI.