Related Experiment Video
Updated: May 12, 2026

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
Published on: January 13, 2018
Neurocognitive effects following an overnight call shift on faculty anesthesiologists
L C Chang1, J J Mahoney, S R Raty
1Department of Anesthesiology, Baylor College of Medicine, Houston, TX 77030, USA. lcchang@bcm.edu
Physician sleep deprivation from overnight call significantly impairs learning and memory performance. While other cognitive functions remained unaffected, the impact on these critical areas warrants further investigation for patient safety.
Area of Science:
- Neuroscience
- Medical Education
- Cognitive Psychology
Background:
- Sleep deprivation poses risks to patient care and physician well-being.
- Accreditation Council for Graduate Medical Education mandates resident work hour limits.
- Faculty anesthesiologists' neurocognitive performance after overnight call was investigated.
Purpose of the Study:
- To assess the neurocognitive effects of overnight call duty on faculty anesthesiologists.
- To identify specific cognitive domains impacted by sleep deprivation in a clinical setting.
Main Methods:
- Eleven faculty anesthesiologists participated in the study.
- Computerized tests evaluated working memory, verbal learning, and concentration.
- Cognitive tests were administered post-call and after a normal rest period.
Main Results:
- A significant decline in learning and memory performance was observed after overnight call (P=0.04).
- No significant differences were found in working memory or sustained attention.
- Pre-call performance did not differ significantly from control conditions.
Conclusions:
- Overnight call duty leads to a significant reduction in learning and memory capabilities.
- Impact on other cognitive functions may be influenced by practice effects or call variability.
- The clinical significance of these performance changes requires further study.
Related Concept Videos
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Stages of General Anesthesia
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...