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Is atrial electromechanical coupling delayed in patients with secundum atrial septal defect?
Mehmet Burhan Oflaz1, Hekim Karapinar, Zekeriya Kucukdurmaz
1Department of Pediatric Cardiology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey. mburhanoflaz@gmail.com
Insights
Atrial electromechanical coupling time (AEMCT) was investigated in patients with atrial septal defect (ASD). This study found no significant differences in intra- and inter-AEMCT between ASD patients and controls.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
- Echocardiography
Background:
- Limited published data exists on atrial electromechanical coupling time (AEMCT) in atrial septal defect (ASD) patients.
- Tissue Doppler imaging (TDI) is a key method for assessing cardiac function.
Purpose of the Study:
- To investigate the relationship between atrial septal defect (ASD) and atrial electromechanical coupling time (AEMCT).
- To determine if AEMCT differs in patients with ASD compared to healthy individuals.
Main Methods:
- A total of 35 ASD patients and 22 healthy controls were enrolled.
- Atrial electromechanical coupling time (AEMCT) was measured using tissue Doppler imaging (TDI) at the mitral and tricuspid annuli.
- Specific intervals (PA-lateral, PA-septal, PA-tricuspid) and differences (intra- and inter-AEMCT) were calculated.
Main Results:
- While some AEMCT intervals were longer in ASD patients, the differences were not statistically significant compared to controls.
- No significant differences were observed in inter-atrial, intra-right atrial, or intra-left atrial AEMCT between groups.
- ASD diameter and total septum length did not correlate with AEMCT measurements.
Conclusions:
- Intra- and inter-atrial electromechanical coupling time (AEMCT) are not significantly increased in patients with atrial septal defect (ASD).
- No association was found between ASD diameter and AEMCT indices.
Background:
There is no available published information about the atrial electromechanical coupling time (AEMCT) in patients with atrial septal defect (ASD). The aim of this study was to investigate the relationship between ASD and AEMCT obtained by tissue Doppler imaging (TDI).
Methods:
A total of 35 patients with ASD and 22 healthy controls were included in the study. The time intervals from the onset of the P-wave on the surface electrocardiogram to the beginning of the late diastolic A-wave (PA) representing AEMCT were obtained from the lateral mitral annulus, septal mitral annulus, and right ventricular (RV) tricuspid annulus, and named PA-lateral, PA-septal, and PA-tricuspid, respectively. The difference between PA-septal and PA-tricuspid, PA-lateral and PA-septal, and PA-lateral and PA-tricuspid were defined as intra-right AEMCT, intra-left AEMCT, and inter- AEMCT, respectively.
Results:
PA-tricuspid, PA-septal, and PA-lateral values were longer in patients with ASD when compared with the controls, but did not reach statistical significance (39.9 ± 19.1 vs. 37.2 ± 15.5, P = 0.952; 49.6 ± 14.0 vs. 45.4 ± 11.1, P = 0.826 and 60.3 ± 16.3 vs. 59.7 ± 12.5, P = 0.437, respectively). There were no significant differences between the ASD and control groups in terms of inter-atrial, intra-right atrial, and intra-left AEMCT (21.3 ± 2.3 vs. 20.8 ± 4.6, P = 0.957; 9.7 ± 3.3 vs. 6.9 ± 1.3, P = 0.723 and 13.6 ± 4.7 vs. 10.9 ± 4.5, P = 0.518, respectively). Furthermore, ASD diameter and total septum length did not correlate with AEMCT.
Conclusion:
Both intra- and inter-AEMCT were not increased in patients with ASD than control subjects. In addition, we found no association between the ASD diameter and indices of AEMCT in patients with ASD.
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