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Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
Published on: July 29, 2021
Commentary on headache currents articles by Alhazzani and Goddeau.
1Division of Developmental Disabilities, Nebraska Department of Health and Human Services, Lincoln, Nebraska, USA.
Headache
|April 19, 2013
Summary
Headaches can signal cerebrovascular disease, especially hemorrhagic types. Migraine with aura may increase stroke risk, with links to cerebrovascular disease being causal, coincidental, or co-morbid.
Area of Science:
- Neurology
- Vascular Neurology
Background:
- Headache is a recognized symptom associated with cerebrovascular diseases.
- Specific headache disorders, such as migraine with aura, are increasingly linked to stroke risk.
Purpose of the Study:
- To explore the complex relationship between headache disorders and cerebrovascular diseases.
- To elucidate the potential causal, coincidental, or co-morbid nature of these associations.
Main Methods:
- Literature review and synthesis of existing research on headache and cerebrovascular events.
- Analysis of epidemiological data and clinical case studies.
Main Results:
- Headache is a prominent symptom in hemorrhagic cerebrovascular disease.
- Migraine with aura is identified as a significant risk factor for both ischemic and potentially hemorrhagic stroke.
Conclusions:
- The association between migraine and cerebrovascular disease is multifaceted, encompassing causal, coincidental, and co-morbid pathways.
- Understanding these links is crucial for accurate diagnosis and risk stratification in patients presenting with headache.
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