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Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Off-pump axillo-coronary artery bypass: a simple approach for high-risk myocardial revascularization
Daniel Grandmougin1, Juan-Pablo Maureira, Antonio Fiore
1Department of Cardiovascular Surgery and Heart Transplantation, ILCV Louis-Mathieu, CHU-Nancy, Vandoeuvre-lès-Nancy, France. d.grandmougin@chu-nancy.fr
Insights
This case study presents a novel surgical approach for complex coronary artery disease. An off-pump axillo-coronary artery bypass and stenting successfully relieved angina in a patient with prior surgeries and complications.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Case Reports
Background:
- Recurrent angina after multiple coronary artery bypass grafting (CABG) procedures presents a significant clinical challenge.
- Previous sternotomy and mediastinitis can increase the complexity and risks associated with repeat cardiac surgery.
- Severe aortic calcification further complicates reoperative CABG strategies.
Observation:
- A 66-year-old male experienced worsening angina post-second CABG, which was complicated by mediastinitis.
- Coronary angiography showed a occluded left anterior descending (LAD) artery bypass graft, a patent native LAD, and a stenotic circumflex artery.
- The patient had severely calcified ascending aorta.
Findings:
- An off-pump axillo-coronary artery bypass to the LAD was successfully performed.
- Simultaneous stenting of the stenotic circumflex artery was completed.
- This combined approach simplified the complex revascularization and mitigated operative risks.
Implications:
- Off-pump axillary artery bypass combined with percutaneous coronary intervention offers a viable alternative for complex, reoperative coronary artery disease.
- This strategy may reduce morbidity and mortality in high-risk patients with challenging anatomy.
- The patient remained symptom-free at 52-month follow-up, indicating durable results.
Abstract:
We report the case of a 66-year-old male with increasing angina occurring after two previous coronary artery surgery procedures. The second operation had been complicated by severe mediastinitis necessitating surgical drainage, and sternal stabilization. Angiography revealed an occlusion of the LAD bypass with a patent LAD associated with a stenotic circumflex coronary artery. The ascending aorta was severely calcified. An off-pump axillo-LAD coronary artery bypass was safely performed in conjunction with stenting of the circumflex artery. This approach dramatically simplified the procedure and reduced the operative risk. At the 52-month follow-up, the patient is free of any angina symptoms.
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