Related Experiment Videos
A glimpse of vitamin D status in Mainland China
Weiguo Zhang1, Elisabeth Stoecklin, Manfred Eggersdorfer
1DSM Nutritional Products, Human Nutrition and Health, Beijing, China and Kaiseraugst, Switzerland. weiguo.zhang@dsm.com
Abstract:
As an essential dietary micronutrient, vitamin D plays a pivotal role in promoting calcium absorption in the intestine and maintaining a healthy skeletal system throughout life. Beyond bone health, an emerging volume of scientific studies shows that vitamin D also may provide cardiovascular, metabolic, and immunologic benefits and reduce mortality. To our knowledge, in mainland China no national surveys have been conducted to date to depict the overall vitamin D status in the population. Therefore, the purpose of this contribution was to provide the best possible evaluation of vitamin D deficiency/insufficiency in China by reviewing publications that measured plasma/serum 25-hydroxyvitamin-D (25[OH]D) levels in various age groups and in different areas of China from January 2000 to June 2012. From these investigations conducted throughout the country and from newborns to adults to the elderly, it has been found that vitamin D deficiency/insufficiency is prevalent in the Chinese population in almost all age groups and areas if individuals are not taking vitamin D-fortified products/supplements or are lacking sufficient sunshine exposure. Some studies showed severe deficiency (25[OH]D <25 nmol/L) in Nanjing (north latitude 31) during the winter months and in Beijing (north latitude 40) in the fall. This unoptimistic situation represents a significant but modifiable public health risk that deserves greater attention and more efficient and timely management.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...