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Published on: January 26, 2019
Electrical control of kinesin-microtubule motility using a transparent functionalized-graphene substrate
Eunji Kim1, Kyung-Eun Byun, Dong Shin Choi
1Department of Biophysics and Chemical Biology, Seoul National University, Seoul, Korea.
Abstract:
We report a new strategy to selectively localize and control microtubule translocation via electrical control of microtubules using a microfabricated channel on a functionalized-graphene electrode with high transparency and conductivity. A patterned SU-8 film acts as an insulation layer which shields the electrical field generated by the graphene underneath while the localized electric field on the exposed graphene surface guides the negatively charged microtubules. This is the first report showing that functionalized graphene can support and control microtubule motility.
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