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Related Concept Videos

Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
Prescription, Nonprescription and Orphan Drugs01:02

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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
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Psychosurgery

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In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

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Related Experiment Video

Updated: May 12, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

[Off-label prescriptions in acute psychiatry: a practice-based evaluation].

R Hoff1, A W Braam

  • 1Juliana Kinderziekenhuis, Den Haag.

Tijdschrift Voor Psychiatrie
|April 19, 2013
PubMed
Summary
This summary is machine-generated.

Off-label medication is common in acute psychiatry, with 41% of prescriptions in one emergency service being off-label, primarily for antipsychotics and benzodiazepines to manage aggression, agitation, and sleep issues.

Related Experiment Videos

Last Updated: May 12, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

Area of Science:

  • Psychiatry
  • Pharmacology

Context:

  • Off-label medication use is prevalent in acute psychiatric settings.
  • Literature review reveals limited data on off-label prescribing in acute psychiatry specifically.

Purpose:

  • To identify indications for off-label prescriptions in psychiatric literature.
  • To assess the utilization of off-label medications within an acute psychiatric emergency service.

Summary:

  • A systematic literature search and patient record evaluation were conducted.
  • 41% of medications prescribed during initial emergency psychiatric contacts were off-label, mainly antipsychotics and benzodiazepines for aggression, agitation, and sleep disturbances.
  • Broader interpretations of off-label use yielded varying percentages, highlighting the need for clear documentation.

Impact:

  • Findings underscore the frequent use of off-label medications in acute psychiatric care.
  • Recommendations include clear documentation of off-label prescription rationale and the development of new medical guidelines.