Resilience in the proteomics data ecosystem: how the field cares for its data

Area of Science:

• Life Sciences
• Proteomics

Background:

• Public data dissemination is crucial in life sciences.
• Proteomics data sharing has increased, with early downstream applications emerging.
• Recent repository closures highlight the fragility of data archiving efforts.

Purpose of the Study:

• To examine the proteomics data ecosystem in detail.
• To address concerns arising from the closure of data repositories.

Main Methods:

• Review of current proteomics data sharing practices.
• Analysis of the impact of repository failures.
• Discussion of data rescue and alternative solutions.

Main Results:

• Proteomics data sharing is expanding rapidly.
• The demise of repositories like NCBI Peptidome and ProteomeCommons Tranche has been noted.
• Successful data rescue efforts for Peptidome data have been undertaken.

Conclusions:

• The proteomics data ecosystem requires careful consideration due to its increasing importance.
• Ensuring the long-term availability and accessibility of shared proteomics data is essential.
• Proactive strategies are needed to build a more robust data-sharing infrastructure.