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Updated: May 12, 2026

Introductory Analysis and Validation of CUT&RUN Sequencing Data
Published on: December 13, 2024
Sequence squeeze: an open contest for sequence compression
Richard Cg Holland1, Nick Lynch
1Eagle Genomics Ltd, Babraham Research Campus, Cambridge, CB22 3AT, UK. richard.holland@eaglegenomics.com.
Abstract:
Next-generation sequencing machines produce large quantities of data which are becoming increasingly difficult to move between collaborating organisations or even store within a single organisation. Compressing the data to assist with this is vital, but existing techniques do not perform as well as might be expected. The need for a new compression technique was identified by the Pistoia Alliance who commissioned an open innovation contest to find one. The dynamic and interactive nature of the contest led to some novel algorithms and a high level of competition between participants.
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