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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
Published on: December 21, 2019
Hemolytic uremic syndrome caused by enteroviral infection
Ming-Dar Lee1, Chin-Yuan Tzen, Chun-Chen Lin
1Department of Pediatrics, Hsinchu Mackay Memorial Hospital, Hsinchu, Taiwan.
Abstract:
A 4-year-old boy presented with enteroviral infection complicated with atypical hemolytic uremic syndrome (aHUS). Enterovirus RNA was detected by reverse transcription polymerase chain reaction (RT-PCR) of both blood and kidney biopsy specimens. A survey of the complement system did not reveal a specific complement defect. Supportive therapy with blood components transfusion, plasma therapy, and immunosuppressants was administered, however, renal function did not recover. The results of this report demonstrate that the enterovirus is the cause of aHUS.
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