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Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
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Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...

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Related Experiment Video

Updated: May 12, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Retroperitoneal fibrosis.

Paul J Scheel1, Nancy Feeley

  • 1Division of Nephrology, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Room 416, Baltimore, MD 21205, USA. Pscheel1@jhmi.edu

Rheumatic Diseases Clinics of North America
|April 20, 2013
PubMed
Summary
This summary is machine-generated.

Retroperitoneal fibrosis (RPF) involves inflammation and scarring in the retroperitoneal space. Recent management shifts from surgery to immunosuppressive therapies targeting immune system modulation.

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Published on: July 19, 2018

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Last Updated: May 12, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

Area of Science:

  • Nephrology
  • Urology
  • Immunology

Background:

  • Retroperitoneal fibrosis (RPF) presents with inflammation and fibrosis in the retroperitoneal space.
  • No standardized diagnostic criteria currently exist for RPF.
  • Traditional treatments focused on surgical relief of ureteric obstruction.

Purpose of the Study:

  • To review recent advancements in the understanding and management of RPF.
  • To cover classification, epidemiology, pathophysiology, pathology, imaging, and treatment of RPF.

Main Methods:

  • Literature review of recent studies on Retroperitoneal Fibrosis.
  • Focus on shifts in diagnostic and therapeutic approaches.

Main Results:

  • Management has evolved from surgical interventions to immunosuppressive therapies.
  • Newer approaches aim to modulate the immune system's role in RPF.

Conclusions:

  • RPF management is transitioning towards immune-modulating strategies.
  • Further research is needed to refine classification, diagnosis, and treatment protocols.