Different sensitivities of Vero cells from two sources to avian reoviruses

Four strains of avian reovirus were each titrated in two batches of Vero cells (A and B) from different sources and different media recommended for each batch. For each strain, variations in titre were observed under the different cultural conditions. In one case the discrepancy between the titre in A cells with medium recommended for B cells, and B cells with A medium was 2.1 log10. Attention is drawn to the possibility that important differences in sensitivity may exist between batches of Vero cells from different sources and these may be exaggerated by the use of different media.