Related Experiment Video
Updated: May 12, 2026

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Relationship between medication event rates and the Leapfrog computerized physician order entry evaluation tool.
Alexander A Leung1, Carol Keohane, Stuart Lipsitz
1Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts 02120-1613, USA.
The Leapfrog CPOE evaluation tool effectively monitors computerized physician order entry (CPOE) performance. Higher Leapfrog scores correlate with reduced preventable adverse drug events (ADE), improving patient safety.
Area of Science:
- Health Informatics
- Patient Safety
- Clinical Quality Improvement
Background:
- Computerized Physician Order Entry (CPOE) systems are crucial for medication safety.
- The Leapfrog CPOE evaluation tool aims to assess the effectiveness of CPOE implementation.
- Monitoring CPOE performance is essential for identifying and mitigating risks.
Purpose of the Study:
- To evaluate the relationship between Leapfrog CPOE evaluation tool scores and rates of preventable adverse drug events (ADE) and potential ADE.
- To determine if Leapfrog scores can serve as a reliable indicator of CPOE system performance in reducing ADE.
Main Methods:
- A cross-sectional study involving 1000 adult admissions across five community hospitals.
- Data collected from October 2008 to September 2010.
- Comparison of observed ADE rates with Leapfrog CPOE evaluation tool scores.
Main Results:
- Leapfrog scores showed a strong correlation with preventable ADE rates.
- A 5% increase in Leapfrog scores predicted a 43% relative reduction in preventable ADE.
- Every 5% increase in Leapfrog scores predicted approximately four fewer preventable ADE per 100 admissions.
Conclusions:
- The Leapfrog CPOE evaluation tool is a valuable instrument for monitoring CPOE performance post-implementation.
- Leapfrog scores can help identify hospital vulnerabilities and guide quality improvement efforts in medication safety.
Related Concept Videos
Methods of Documentation VII: EMR
Methods of Documentation II: POMR
Dosage Regimens: Partial Pharmacokinetic Parameters
Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmaceutical Poisoning: Potential Scenarios