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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Videos

Does acute primary angle-closure cause an increased choroidal thickness?

Wei Wang1, Minwen Zhou, Wenbin Huang

  • 1Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University, Guangzhou, People's Republic of China.

Investigative Ophthalmology & Visual Science
|April 20, 2013
PubMed
Summary
This summary is machine-generated.

Eyes with acute primary angle-closure (APAC) show significantly greater choroidal thickness compared to primary angle-closure suspect (PACS) eyes. This finding in APAC patients highlights potential structural differences in the choroid.

Keywords:
acute primary angle-closurechoroidal thicknessprimary angle-closure suspect

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Anatomy
  • Medical Imaging

Background:

  • Acute primary angle-closure (APAC) is a serious ophthalmic condition.
  • Understanding the structural changes in APAC is crucial for diagnosis and management.
  • Choroidal thickness variations may play a role in the pathophysiology of angle-closure glaucoma.

Purpose of the Study:

  • To compare choroidal thickness between eyes diagnosed with acute primary angle-closure (APAC) and their fellow eyes with primary angle-closure suspect (PACS).
  • To investigate macular and peripapillary choroidal thickness differences in unilateral APAC patients.

Main Methods:

  • Utilized enhanced depth imaging-optical coherence tomography (EDI-OCT) for measurements.
  • Included 21 participants with unilateral APAC and their fellow eyes (PACS).
  • Compared average macular and peripapillary choroidal thickness between APAC and PACS eyes.

Main Results:

  • Choroidal thickness was greatest at the subfovea in both APAC and PACS eyes.
  • APAC eyes exhibited significantly greater macular choroidal thickness than PACS eyes at most locations.
  • Mean subfoveal choroidal thickness was 349.0 μm in APAC eyes versus 308.1 μm in PACS eyes (P < 0.005).
  • Subfoveal choroidal thickness correlated positively with APAC diagnosis and diastolic blood pressure.

Conclusions:

  • Eyes with acute primary angle-closure (APAC) demonstrate increased macular choroidal thickness compared to primary angle-closure suspect (PACS) eyes, even after intraocular pressure reduction.
  • The underlying reasons for this observed difference in choroidal thickness require further investigation.