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Updated: May 12, 2026

Chromatin Immunoprecipitation (ChIP) using Drosophila tissue
Published on: March 23, 2012
Comment on "Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters"
Tobias Straub1, Peter B Becker
1Bioinformatic Unit, Adolf-Butenandt-Institute and Center for Integrated Protein Science, Ludwig-Maximilians-University, D-80336 Munich, Germany. tobias.straub@lmu.de
Abstract:
Conrad et al. (Reports, 10 August 2012, p. 742) reported that Drosophila dosage compensation might largely be due to increased recruitment of RNA polymerase II to promoters. A reassessment of the numerical operations revealed that the authors' calculations are severely confounded by an inappropriate numerical procedure. A rectified analysis strongly suggests that the authors' conclusions are not supported by their data.
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