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Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
Electron microscopy of the morphological changes in rat viscera during experimental hyperthermic shock
1Department of Clinical Anatomy and Surgical Techniques, Chair of Anatomy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania. vlad_marius@hotmail.com
Abstract:
Hyperthermic shock is a thermoregulatory disorder that affects living organisms that are acutely or chronically exposed to high temperatures or when performing intense physical activity in a hot environment. In this paper, we will show the changes embodied in hyperthermic shock caused by multiple injuries to vital organs in Wistar rats that were suddenly exposed to high temperatures of up to 410 for about 10-15 minutes, their central temperature rising above 40.60C. This process resulted in multiple injuries of the vital organs, evidenced by electron microscopy. In addition, this suggested that most changes caused by hyperthermic shock are incompatible with life.

