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Related Experiment Video

Updated: May 12, 2026

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa
08:17

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Published on: September 27, 2018

Submucosal implantation of soft tissue expanders does not affect microcirculation.

Doğan Kaner1, Han Zhao, Hendrik Terheyden

  • 1Department of Periodontology, University of Witten/Herdecke, Witten, Germany.

Clinical Oral Implants Research
|April 23, 2013
PubMed
Summary

Submucosal tissue expanders minimally impact blood flow, with microcirculation returning to normal levels within one day. This temporary effect may contribute to successful outcomes in reconstructive surgery.

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Area of Science:

  • Oral surgery
  • Biomaterials science
  • Vascular biology

Background:

  • Severely resorbed edentulous ridges pose challenges in dental implantology.
  • Tissue expanders are used to augment soft tissue volume for reconstruction.
  • Understanding microcirculatory effects is crucial for evaluating new biomaterials.

Purpose of the Study:

  • To assess the impact of self-filling osmotic tissue expanders on mucosal microcirculation.
  • To evaluate the duration of microcirculatory disturbances following submucosal implantation.

Main Methods:

  • Ten beagle dogs underwent mandibular premolar extraction and soft tissue reduction.
  • Self-filling osmotic tissue expanders (0.7 ml final volume) were implanted submucosally.
  • Laser Doppler flowmetry measured mucosal microcirculation at multiple time points.
Keywords:
Laser Doppler flowmetrymicrocirculationsoft tissue expansiontissue expanders

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Last Updated: May 12, 2026

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Main Results:

  • Local anesthesia significantly decreased blood flow (P=0.006).
  • No significant additional decrease in blood flow occurred post-surgery.
  • Microcirculation recovered to baseline levels within 1 day, with slight increases at days 1 and 3.

Conclusions:

  • Submucosal implantation of these tissue expanders causes only transient microcirculatory disturbance.
  • The minimal and temporary impairment of perfusion supports their clinical efficacy.
  • This finding aids in understanding the success of submucosal tissue expander applications.