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PARP inhibitors: polypharmacology versus selective inhibition

Torun Ekblad1, Emidio Camaioni, Herwig Schüler

  • 1Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Stockholm, Sweden.

The FEBS Journal
|April 23, 2013
PubMed

Keywords:
ADP-ribosyltransferasesPARPcancerdrug designpoly(ADP-ribose) polymerasespolypharmacologypromiscuityselective inhibitorsselectivitystructure-based drug design

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