Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 12, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Focal brachytherapy for selected low-risk prostate cancers: a pilot study.

Jean-Marc Cosset1, Xavier Cathelineau, Georges Wakil

  • 1Department of Oncology/Radiotherapy, Institut Curie, Paris, France. jean-marc.cosset@curie.net

Brachytherapy
|April 23, 2013
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Focal Therapy for Prostate Cancer: A Treatment Option Reserved for the Ideal Candi-date?

International braz j urol : official journal of the Brazilian Society of Urology·2026
Same author

ProBIOPSY: A Multidisciplinary International Consensus on Standards for Prostate Biopsy.

European urology·2026
Same author

Evidence Thresholds for Novel Therapeutic Strategies in Prostate Cancer: A Consensus Statement from the Prostate Cancer Committee of the French Urological Association.

The French journal of urology·2026
Same author

Shifting risk profile in radical prostatectomy over 18 years: A bicentric French study of 8,358 patients.

The French journal of urology·2026
Same author

The evolution of radical prostatectomy: a scoping review on surgical techniques and integration of surgeon-assisting concepts into the surgical workflow.

Frontiers in surgery·2026
Same author

Results of the Randomized Phase 3 AFU-GETUG-20 Trial Evaluating Adjuvant Leuprorelin Acetate After Radical Prostatectomy in Men with High-risk Localized Prostate Cancer.

European urology oncology·2026

Focal brachytherapy for localized prostate cancer is feasible and shows low acute toxicity. This targeted approach demonstrated improved erectile function recovery and minimal urinary or rectal side effects in selected patients.

Area of Science:

  • Oncology
  • Radiation Oncology
  • Urology

Background:

  • Prostate cancer treatment often involves whole-gland therapies.
  • Focal brachytherapy offers a targeted approach for localized tumors.
  • Patient selection is critical for focal treatment success.

Purpose of the Study:

  • To assess the feasibility of focal brachytherapy for select prostate cancer patients.
  • To evaluate the early toxicity profile of this focal treatment modality.
  • To compare outcomes with whole-prostate brachytherapy.

Main Methods:

  • Twenty-one highly selected patients with localized prostate cancer underwent focal brachytherapy.
  • Treatment involved real-time implantation of Iodine-125 seeds with dynamic dose calculation.

More Related Videos

Focal Laser Ablation of Prostate Cancer: An Office Procedure
11:07

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Related Experiment Videos

Last Updated: May 12, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Focal Laser Ablation of Prostate Cancer: An Office Procedure
11:07

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

  • A prescribed dose of 145Gy was delivered to the focal tumor volume.

    • Main Results:

    • The mean treated prostatic volume was 34%.
    • Focal brachytherapy showed borderline reduced urinary toxicity and better erectile function recovery compared to whole-gland treatment.
    • Minimal rectal and urinary incontinence were observed.

    Conclusions:

    • Focal brachytherapy is a feasible treatment for carefully selected prostate cancer patients.
    • The procedure is associated with low acute toxicity.
    • Further studies are required to confirm long-term tumor control and toxicity.