Perforated gastrointestinal stromal tumor in Meckel's diverticulum treated laparoscopically

Gastrointestinal stromal tumors (GIST) can represent a source of substantial gastrointestinal hemorrhage. Bleeding is described as a frequent cause of clinical presentation and commonly patients received surgical treatment on an urgent basis to drain the hematoma. However, a literature review has shown that perforation with peritonitis is very uncommon and rarely reported. These tumors are usually located in the stomach, and primary ileal and Meckel's localization is rare, occurring in less than 10% of cases in many series. In the English literature, we have found seven well-reported cases of GIST in a Meckel's diverticulum that presented with perforation and peritonitis; these case were found through a MEDLINE search of the terms: "perforated" GISTs in "Meckel's" GISTs. Herein, we describe a rare case of a perforated GIST in Meckel's diverticulum that caused severe peritonitis and that was treated with minimally invasive surgery.