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Updated: May 12, 2026

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Published on: June 2, 2014
Chronic migraine
1Emergency Headache Centre, Lariboisière Hospital, 2, rue Ambroise-Paré, 75010 Paris, France. dominique.valade@lrb.aphp.fr
Chronic migraine (CM) affects 2% of the global population, characterized by 15+ headache days monthly. Treatment involves education, lifestyle changes, and therapies to manage this disabling condition.
Area of Science:
- Neurology
- Headache Medicine
Background:
- Chronic migraine (CM) is defined by the International Classification of Headache Disorders (ICHD-2R) as 15 or more headache days per month.
- Approximately 2% of the global population experiences chronic migraine, a condition distinct from episodic migraine (EM) by headache frequency and disability.
- Medication overuse is a common comorbidity in chronic migraine patients.
Purpose of the Study:
- To summarize the definition, prevalence, and treatment approaches for chronic migraine.
- To highlight the key differences between chronic and episodic migraine.
- To emphasize the multifactorial nature of chronic migraine management.
Main Methods:
- Review of the International Classification of Headache Disorders, 2nd edition, revised (ICHD-2R) criteria for chronic migraine.
- Analysis of global prevalence data for chronic migraine.
- Overview of established and emerging treatment strategies for chronic migraine.
Main Results:
- Chronic migraine is diagnosed with at least 15 headache days per month, with 8 meeting migraine criteria or responding to specific treatment.
- The condition impacts approximately 2% of the world's population.
- Effective management requires a comprehensive approach including education, lifestyle adjustments, trigger identification, and behavioral/pharmacologic therapies.
Conclusions:
- Chronic migraine is a significant global health issue requiring careful diagnosis and management.
- Distinguishing CM from EM is crucial for appropriate treatment planning.
- Integrated treatment strategies are essential for improving outcomes in patients with chronic migraine and medication overuse.
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